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Journal Clubs and Research Seminars
Advanced undergraduates are also encouraged to attend Journal Clubs. These are informal, weekly sessions which cover a specific research topic. Each week a recent research paper is discussed. Several journal clubs run concurrently each semester.
If you have questions concerning the Molecular Biology and Biochemistry major they can be addressed to any faculty member in the MB&B Department.
MBB 286/586 Journal Club
This Journal Club includes the presentation and discussion of recent findings in the field of molecular and cellular biology. MB&B 286/586 is described on the bulletin board outside of the Molecular Biology and Biochemistry Department Office.
Mondays 12:00 PM to 1:00 PM
201 Shanklin
Coordinator: Scott Holmes
MBB 209 Research Frontiers in Molecular Biology and Biochemistry
Fridays 2:30 PM to 3:50 PM
201 Shanklin
Coordinators: Manju Hingorani and Ishita Mukerji
This course of weekly discussions of current research is for students who have completed the MB&B or BIOL introductory series. Discussions will be informal in nature and cover topics of current interest in molecular biology and biochemistry, emphasizing possibilities for future research areas for the students.
January 29 Mukerji with Olga Buzovetsky
February 5 Erika Taylor
February 12 Holmes Lab with Samantha Schilit
February 19 Don Oliver with Jennifer Michtavy or Elena Georgieva
February 26 Michael McAlear with James Arnone
March 5 Bob Lane
March 26 Amy MacQueen
April 2 Russu Laboratory with Yuegao 'Golden' Huang
April 9 Manju Hingorani with Nora Biro and Chris Doucette
April 16 Jan Naegele
April 23 Rich Olson and Kelsey Tyssowski
April 30 Lunch with professors! and Wrap up
MB&B 308/508 The Molecular Biophysics Journal Club
The Molecular Biophysics Journal Club (MB&B 307/507) is a weekly gathering of all students, research associates and faculty associated with the program for critical consideration and discussion of research described in the current literature. Here, in addition to exposure to advanced subject matter, students gain experience with research design, and presentation and discussion skills. Molecular Biophysics Journal Club is a centerpiece of the Biophysics program and regular participation is required for students in the program. Questions about the Molecular Biophysics Program can be directed to David Beveridge (dbeveridge@wesleyan.edu).
Wednedays 1:10 PM to 2:30 PM
137 Science Center
Coordinators: Ishita Mukerji and Dave Beveridge
|
Dates |
Papers |
Presenters |
|
Feb 3 |
Neutron Structure of Human Carbonic Anhydrase II: Implications for Proton Transfer Fisher et al., Biochemistry (2010) 49, 415421 DOI: 10.1021/bi901995n A Short, Strong Hydrogen Bond in the Active Site of Human Carbonic Anhydrase II Avvaru et al., Biochemistry (2010) 49, 249251 DOI: 10.1021/bi902007b |
Sam Berman |
|
Feb 17* |
A Statistical Thermodynamic Model of the Protein Ensemble. Hilser, et al., Chem. Rev. (2006) 106, 1545-1558 DOI: 10.1021/cr040432 Functional residues serve a dominant role in mediating the cooperativity of the protein ensemble Can allosteric regulation be predicted from structure? Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble |
Anushi Sharma |
|
Mar 24 |
Functional Anthology of Intrinsic Disorder. 1. Biological Processes and Functions of Proteins with Long Disordered Regions Functional
Anthology of Intrinsic Disorder. 2. Cellular Components, Domains,
Technical Terms, Developmental Processes, and Coding Sequence
Diversities Correlated with Long Disordered Regions Functional
Anthology of Intrinsic Disorder. 3. Ligands, Post-Translational
Modifications, and Diseases Associated with Intrinsically Disordered
Proteins April 1: Keith Dunker seminar: MBB department |
Becky Lee |
|
April 7 |
Optimization of bacteriorhodopsin for bioelectronic devices Biomolecular Electronics: Protein-Based Associative Processors and Volumetric Memories April 9: Robert Birge seminar: Chemistry Department |
Swastik De |
|
April 21 |
The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex A
Slow ATP-induced Conformational Change Limits the Rate of DNA Binding
but Not the Rate of Clamp Binding by the Escherichia coli Complex
Clamp Loader Clamp loaders and replication initiation. |
Andrew Moreno |
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May 5 |
Open discussion |
|
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*Feb 24 no class because of Biophysical Society Meeting; Mar 10 and Mar 17 no class Spring Break |
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MB&B558 Research Seminars in Molecular Biology and Biochemistry
The course involves weekly formal presentations by graduate students on their research projects. The presentations include description of experimental design, approaches and methods, analysis, conclusions, and future directions, as well as details of problems encountered and potential solutions. Active discussion among the participants is encouraged to develop science communication skills, to share new ideas and interpretations, and to introduce novel approaches that facilitate progress. First-year graduate students are expected to present a summary of the work accomplished during the rotation period. Students working on advanced research projects are expected to present more formal seminars to practice public-speaking skills and prepare to defend their dissertation research. The class meets for a 60-minute period once every week. This course is required of all graduate students.
Wednesdays 4:00 - 5:00 PM
201 Shanklin
Coordinator: Rich Olson
February 3 Nidhi Pathak (Lane Lab)
February 10 Tesfazghi Zeraslase/Seda Kilinc (Lane Lab - class will end at 5:30)
February 17 No seminar
February 24 Asmita Lazarus (Holmes Lab)
March 3 Tina Motwani (Holmes Lab)
March 10 Spring Break
March 17 Spring Break
March 24 Rebecca Ryznar (Holmes Lab)
March 31 Upasna Sharma (Holmes Lab)
April 7 Yan Li (Mukerji Lab)
April 14 Andrew Moreno (Mukerji Lab)
April 21 Noah Biro, Samantha Schilit (BA/MA)
April 28 Olga Buzovetsky, Samuel Cohen (Senior Theses)
May 5 Pritam Mukherjee, Swastik De (Rotation Students)
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